An analysis of the cable properties of frog ventricular myocardium.

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Abstract
The passive and active electrical parameters of frog ventricular myocardium were measured. The cytoplasmic resistivity was determined by following changes in the resistance of a micro-electrode on penetration of a cell. Unidimensional cable analysis using direct and alternating currents revealed the presence of a single time constant attributed to the surface membrane. Longitudinal impedance measurements indicate that a 2nd time constant is present in the intracellular pathway. The resistance between cells is low so that action potentials can propagate from cell to cell by local circuits. A 3-dimensional cable analysis was performed and compared to a simplified mathematical model which is presented in an appendix and which closely approximates the experimental situation.