THE OCCURRENCE OF EPILEPTIC FITS IN LEUCOTOMIZED PATIENTS RECEIVING CHLORPROMAZINE THERAPY

Abstract
Of 75 chronic mental hospital patients treated with chlorpromazine, 21 had previously undergone a frontal leucotomy, and of these 7 developed epileptic fits during or immediately after chlorpromazine therapy. Only 2 of these had had previous post-leucotomy seizures. E.E.G. studies showed epileptic foci in one or both frontal lobes.