CESSATION OF THERAPY IN CHILDHOOD LEUKEMIA A Survey of 160 Cases from the Nordic Countries

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Abstract
A survey is presented of 160 children from the Nordic countries who had antileukemic therapy discontinued before Nov. 1976. Twenty-seven of the 160 cases (17%) suffered a relapse before May 1977. Sixty-nine cases had therapy stopped in the first 10 mo. of 1976. All cases were reported as acute lymphocytic leukemia. Different therapy schedules were used. Thirty-five cases in sustained remission for more than 3 yr without cessation of therapy are also included in the report, 17 of whom relapsed while still on therapy. CNS or testicular relapse occurred in 21 of the total 44 cases who relapsed after 3 or more years of continuous remission, whether they were on therapy or not.