Similar delivery rates in a selected group of patients, for day 2 and day 5 embryos both cultured in sequential medium: a randomized study.
Open Access
- 1 October 2003
- journal article
- clinical trial
- Published by Oxford University Press (OUP) in Human Reproduction
- Vol. 18 (10) , 2145-2150
- https://doi.org/10.1093/humrep/deg394
Abstract
BACKGROUND: The existence of a real benefit of blastocyst transfer is still a matter of debate. The aim of this study was to compare, in a prospective randomized trial, the outcome of day 2 and day 5 transfer of human embryos cultured in an ‘in‐house’ sequential medium. METHODS: A total of 193 cycles from 171 patients with less than four previous IVF cycles, P < 0.001) respectively. Delivery rates per transfer were 44.1 and 37.1% [P = not significant (NS)], implantation rates were 31.4 and 29.4% (NS) and multiple delivery rates 22 and 36% (NS) for day 2 and day 5 groups respectively. Ten patients (10.1%) had no blastocysts available for transfer. CONCLUSIONS: No clear benefits were observed using blastocyst transfer for patients aged <39 years who had had less than four previous IVF cycle attempts.Keywords
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