Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis.
Open Access
- 1 May 1976
- Vol. 17 (5) , 332-334
- https://doi.org/10.1136/gut.17.5.332
Abstract
The frequency of HLA-A3 and HLA-B14 antigens was significantly higher in a series of 51 patients with idiopathic haemochromatosis than in a control group, being respectively 78-4 versus 27-0% and 25-5 versus 3-4%. This finding strongly supports the suggestion that idiopathic haemochromatosis is a genetic disease and suggests that the gene(s) responsible for the disease may be linked to the histocompatibility genes.Keywords
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