Synthesis of β-Hydroxy Esters by Lithium/Ammonia Reduction of α,β-Epoxy Esters

Abstract
Aliphatic β-hydroxy esters (alkyl 3-hydroxyalkanoates) are conveniently prepared in high yield by regioselective lithium/ammonia reduction of α,β-epoxy esters (alkyl 2,3-epoxyalkanoates).

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