Thyroid Function Tests During the Early Phase of Subacute Thyroiditis

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Abstract
Six patients with subacute thyroditis were followed with serial measurements of T4 [thyroxine], FT4 [free thyroxine] TSH [thyrotropin] and RAI [radioactive iodine uptake] uptake. Five of the 6 underwent TRH [thyrotropin releasing hormone] stimulation early in the course of their illness. All 6 patients had elevated or high normal values for T4 and FT4 at the time of their clinical presentation (mean = 13.8 .mu.g/100 ml and 3.9 ng/100 ml, respectively). RAI uptakes were 1% or less in all 6. TRH testing revealed a suppressed TSH response (mean .DELTA.TSH < 0.1 .mu.U[microunits]/ml) in all 5 patients tested, suggesting hyperthyroidism. After initial studies were performed, 5 patients were treated with L-triiodothyronine (L-T3) and 1 with aspirin. All patients improved over a 2-4 wk period of time, no relapses being noted.

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