Abstract
Studies on multiplication of T. brucei and T. congolense showed that trypanosomes artificially maintained in mice multiply exclusively by longitudinal fission. T. brucei and T. congolense in a rabbit and a guinea-pig as well as in sheep has, in addition to multiplication by binary fission, a developmental cycle which includes leishmanial, leptomonad, crithidial and multinucleated forms. Since some of these forms were seen dividing, we suggest that they may be part of the developmental cycle in the vertebrate host.

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