Abstract
We report a case of fingernail onychomycosis in an immunosuppressed renal transplant patient who was successfully treated with once-weekly fluconazole therapy. Relapse did not develop over the 2-month follow-up period. There were no adverse effects from therapy and the cyclosporin dose did not require adjustment. This case suggests that fluconazole may play a role in the treatment of onychomycosis with once-weekly dosing schedules. Future large-scale clinical trials are indicated to fully evaluate its safety and efficacy in onychomycosis.

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