COMPARATIVE ANTI-INFLUENZA VACCINATION OF SOME GROUPS OF THE POPULATION WITH VACCINES DIFFERING IN VIRUS PURIFICATION LEVEL

  • 1 January 1987
    • journal article
    • research article
    • Vol. 35  (2) , 201-206
Abstract
A total of 1215 persons, divided into 4 groups, were immunized with influenza vaccines A (highly purified, whole-virion), B (subunit, containing H and M), and C (conventional, commercial partly purified by Sharplers centrifugation). Post-vaccination reactions were followed, and serological tests (HI and NI) were performed with serum specimens taken from each vaccine 4 times during and after the vaccination period. The results point to clear superiority of purified and subunit vaccines over the conventional one.

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