FIVE-YEAR ANALYSIS OF ADENOVIRUS 8 ANTIBODY LEVELS IN AN INDUSTRIAL COMMUNITY FOLLOWING AN OUTBREAK OF KERATOCONJUNCTIVITIS
- 1 August 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in American Journal of Epidemiology
- Vol. 110 (2) , 132-140
- https://doi.org/10.1093/oxfordjournals.aje.a112797
Abstract
Serum hemagglutination-inhibition (HI) antibody titers were monitored for five years with samples from 79 keratoconjunctivitis patients with type 8 adenovirus (AV-8) infection. Geometric mean antibody titers declined from 1:161 at the peak of the epidemic to 1:56 after five years. Computerized analysis of the decline in geometric mean antibody titer indicates that most patients will have a serum HI titer of 1:25 by 10 years after their clinical infection. These residual antibody levels and the consistent failure to document re-infection with AV-8 suggest that recurrent episodes of keratoconjunctivitis are caused by adenovirus serotypes other than type 8.Keywords
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- AETIOLOGY OF KERATOCONJUNCTIVITIS IN EPIDEMIC AND NON-EPIDEMIC PERIODS1965
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