Electrophoretic Studies on Cerebrospinal Fluid.

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Abstract
The results of a detailed investigation of the distr. of 2 rapidly migrating components and of other protein components of cerebrospinal fluids has been presented. A component (X-protein) migrating about 20% faster than the albumin could be demonstrated in every fluid by electrophoresis in phosphate at pH 7.85 and ionic strength 0.05. In addition a component (X1) migrating 8-14% faster than the X-protein was observed in 20% of the cases. Analyses of 49 patterns of the most frequently encountered type and 16 atypical patterns are presented. No individual protein component was responsible for the higher protein concn. observed in some of the fluids. A possible relationship between X1 component and the occurrence of convulsion in patients was indicated.