Mutations in the Leucine Zipper Motif and Sterol-sensing Domain Inactivate the Niemann-Pick C1 Glycoprotein
Open Access
- 1 July 1999
- journal article
- Published by Elsevier
- Vol. 274 (31) , 21861-21866
- https://doi.org/10.1074/jbc.274.31.21861
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- Niemann-Pick C1 protein: Obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilizationProceedings of the National Academy of Sciences, 1999
- Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis GeneScience, 1997
- Niemann-Pick C1 Disease Gene: Homology to Mediators of Cholesterol HomeostasisScience, 1997
- Substantial narrowing of the Niemann–Pick C candidate interval by yeast artificial chromosome complementationProceedings of the National Academy of Sciences, 1997
- Leucine Zipper-mediated Dimerization Is Essential for the PTC1 Oncogenic ActivityPublished by Elsevier ,1997
- Sterol Resistance in CHO Cells Traced to Point Mutation in SREBP Cleavage–Activating ProteinCell, 1996
- The “Putative” Leucine Zipper Region of Murine Leukemia Virus Transmembrane Protein (P15e) Is Essential for Viral InfectivityVirology, 1996
- The intracellular targeting and membrane topology of 3-hydroxy-3-methylglutaryl-CoA reductase.Published by Elsevier ,1992
- Type-C Niemann-Pick disease: low density lipoprotein uptake is associated with premature cholesterol accumulation in the Golgi complex and excessive cholesterol storage in lysosomes.Proceedings of the National Academy of Sciences, 1988
- A defect in cholesterol esterification in Niemann-Pick disease (type C) patients.Proceedings of the National Academy of Sciences, 1985