Absolute configuration and biosynthesis of the austalides, meroterpenoid metabolites of Aspergillus ustus: mode of cyclisation of the farnesyl moiety

Abstract
A study of the fate of the hydrogen atoms in the biosynthesis of austalide D using both (13C,2H)- and 2H-labelled mevalonolactones established, in conjunction with absolute configuration as determined by an X-ray crystallographic study, the stereochemical course of cyclisation of the farnesyl-derived moiety.

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