EFFECT OF INTRA-CEREBRAL MICRO-INJECTION OF NALOXONE ON ACUPUNCTURE-ANALGESIA AND MORPHINE-ANALGESIA IN THE RABBIT

  • 1 January 1981
    • journal article
    • research article
    • Vol. 24  (8) , 1166-1178
Abstract
Evidently endogenous opiate-like substances participate in acupuncture analgesia, but their exact sites of action are unknown. Injecting minute amount of narcotic antagonist naloxone into discrete brain areas and assessing its effect on acupuncture analgesia in rabbits showed that nuclei accumbens, amygdala, habenula and periaqueductal grey are the strategic sites for analgesic effect of endogenous opioids. These brain areas are also important in morphine analgesia.

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