A Practical Synthesis of (R)-(+)-Cyclohex-3-enecarboxylic Acid via an Asymmetric Diels-Alder Reaction
- 1 January 1993
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1993 (05) , 475-477
- https://doi.org/10.1055/s-1993-25885
Abstract
The polymerisation which complicates the ethylaluminum dichloride-catalysed asymmetric Diels-Alder reaction between N-propenoylbornane-10,2-sultam [10,10-dimethyl-3-thia-4-azatricyclo-[5.2.1.01,5]decane 3,3-dioxide] and butadiene can be suppressed using galvinoxyl [2,6-di-tert-butyl-α-(3, 5-di-tert-butyl-4-oxo-2,5-cyclohexadien-1-ylidene)-p-tolyloxyl] leading to a practical and large scale synthesis of (R)-(+)-cyclohex-3-enecarboxylic acid.Keywords
This publication has 0 references indexed in Scilit: