ALKALOIDS OF THALICTRUM .27. NEW HYPOTENSIVE APORPHINE-BENZYLISOQUINOLINE DERIVED DIMERIC ALKALOIDS FROM THALICTRUM-MINUS RACE-B

  • 1 January 1978
    • journal article
    • research article
    • Vol. 41  (3) , 271-276
Abstract
The roots of T. minus race B have yielded, in addition to adiantifoline previously isolated by column chromatography from this source, 2 new related alkaloids, thaliadine and thaliadanine. Both were assigned complete structures by spectral methods and by chemical interconversion to adiantifoline or its product. O-Desmethyladiantifoline should have structure 14, rather than the previously reported thaliadanine. All 3 isolated alkaloids show hypotensive activity in rabbits and thaliadanine has antimicrobial activity against Mycobacterium smegmatis.

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