NUCLEAR MAGNETIC RESONANCE AND INFRARED SPECTRA OF DELTA24- AND C-24 SATURATED STEROIDS
- 1 January 1968
- journal article
- research article
- Vol. 9 (1) , 120-+
Abstract
The infrared (IR) and nuclear magnetic resonance (NMR) spectra of 8 A24-steroids and 9 C-24 saturated steroids were examined. NMR spectra allow unambiguous assignment of the biologically important A24-bond; introduction of a A24-bond causes the appearance of peaks at S1.60 and 1.68 associated with the C-26, C-27 isopropylidene methyls, while C-24 saturated steroids of the cholestane series possess peaks at 8 0.82 and 0.91 associated with the C-26, C-27 gemdimethyls. IR spectra show a good correlation between the introduction of a A24_ bond and a marked decrease in intensity of a band at 1365 cm"1. NMR and IR spectra also allow an inference about the presence and location of nuclear double bonds in Ring B of cholesterol precursors.This publication has 12 references indexed in Scilit:
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