Humoral Regulation of Erythropoiesis V. Relationship of Plasma Erythropoietine Level to Bone Marrow Activity

Publisher Website
Google Scholar
Abstract
Data are presented on the rate of appearance and disappearance of erythropoietine. The plasma level of erythropoietine rises promptly in response to hypoxia but on continued exposure declines. In rate with radiation-induced hypoplasia, this fall in erythropoietine titer was modified. Accordingly, it is suggested that the marrow utilizes erythropoietine and the clinical implications are discussed.