Effects of clofibrate with androsterone (atromid) and without androsterone (atromid-S) on blood platelets and lipids in ischaemic heart disease.

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Abstract
The effects of clofibrate with and without androsterone on platelet stickiness and the blood lipids have been studied in 35 men with ischemic heart disease. Both drugs favourably decreased platelet stickiness (p<0. 001), but the effect with clofibrate and androsterone (atromid) was more marked than with clofibrate alone (Atromid-S). Both drugs produced a statistically significant (p<0.001) and similar fall in serum cholesterol; their effects on low density lipoprotein were inconstant. The changes in platelet stickiness and in the lipids appeared to be independent.