The nature of immunity againstBabesia hylomysciandB. microtiinfections in mice

Publisher Website
Google Scholar
Abstract
Mice which have recovered from B. microti infection lose their parasitemia as early as 3 wk after recovery and become solidly immune. This sterile immunity is not affected by splenectomy and may last for the life of the mouse. Mice which have recovered from B. hylomysci infection continue to harbor parasites at a subpatent level and spontaneous relapses were common after recovery. Hence the type of immunity which developed against this parasite is premunition and may last for life. Such immunity was not absolute and considerable parasitemias developed after challenge. Cross-protection occurred between the 2 spp. of parasite.