Recombinant human parainfluenza virus type 2 vaccine candidates containing a 3′ genomic promoter mutation and L polymerase mutations are attenuated and protective in non-human primates
- 21 August 2007
- Vol. 25 (34) , 6409-6422
- https://doi.org/10.1016/j.vaccine.2007.06.028
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- Introducing point and deletion mutations into the P/C gene of human parainfluenza virus type 1 (HPIV1) by reverse genetics generates attenuated and efficacious vaccine candidatesVaccine, 2006
- Live-attenuated intranasal parainfluenza virus type 2 vaccine candidates developed by reverse genetics containing L polymerase protein mutations imported from heterologous paramyxovirusesVaccine, 2005
- Identification of a Recombinant Live Attenuated Respiratory Syncytial Virus Vaccine Candidate That Is Highly Attenuated in InfantsThe Journal of Infectious Diseases, 2005
- Sendai Virus RNA-dependent RNA Polymerase L Protein Catalyzes Cap Methylation of Virus-specific mRNAJournal of Biological Chemistry, 2005
- Demystifying FluMist, a new intranasal, live influenza vaccine.Cleveland Clinic Journal of Medicine, 2003
- Chemical Mutagenesis of Dengue Virus Type 4 Yields Mutant Viruses Which Are Temperature Sensitive in Vero Cells or Human Liver Cells and Attenuated in MiceJournal of Virology, 2001
- Evaluation of a live attenuated bovine parainfluenza type 3 vaccine in two- to six-month-old infantsThe Pediatric Infectious Disease Journal, 1996
- Cold-passaged human parainfluenza type 3 viruses contain ts and non-ts mutations leading to attenuation in rhesus monkeysVirus Research, 1992
- The Role of Parainfluenza Viruses in Inspiratory Difficulties in ChildrenActa Paediatrica, 1988
- A Longitudinal Study of Respiratory Viruses and Bacteria in the Etiology of Acute Otitis Media with EffusionNew England Journal of Medicine, 1982