Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver
Open Access
- 15 March 2008
- journal article
- Published by American Society of Hematology in Blood
- Vol. 111 (6) , 3005-3014
- https://doi.org/10.1182/blood-2007-07-098830
Abstract
Transcription factors such as Scl/Tal1, Lmo2, and Runx1 are essential for the development of hematopoietic stem cells (HSCs). However, the precise meKeywords
This publication has 72 references indexed in Scilit:
- Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancerBlood, 2007
- TAL-1/SCL and Its Partners E47 and LMO2 Up-Regulate VE-Cadherin Expression in Endothelial CellsMolecular and Cellular Biology, 2007
- The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activityProceedings of the National Academy of Sciences, 2007
- CoMoDis: composite motif discovery in mammalian genomesNucleic Acids Research, 2006
- Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemiaBlood, 2006
- SCL/TAL1 expression level regulates human hematopoietic stem cell self-renewal and engraftmentBlood, 2005
- Disruption of differentiation in human cancer: AML shows the wayNature Reviews Cancer, 2003
- Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte DevelopmentCell, 2002
- The SCL gene specifies haemangioblast development from early mesodermThe EMBO Journal, 1998
- Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCLNature, 1995