Zoonotic Filariasis with Lymphedema in an Immunodeficient Infant

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Abstract
INFECTION with filarial parasites (Wuchereria bancrofti, Brugia malayi, and B. timori) that dwell in the lymphatic system produces a range of manifestations, including elephantiasis,1 which usually develops in adulthood. Related brugian filarial species, ordinarily parasitic in animals, can cause local lymphadenopathy in human beings.2 3 4 5 We describe an infant with immunodeficiency who had severe lymphedema due to filarial infection with a zoonotic brugia species.Case ReportThe patient, born in Oklahoma to parents who were first cousins, was hospitalized with pneumonia at the age of seven months. He was found to have hypogammaglobulinemia (IgG, 10 mg per deciliter . . .

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