Distribution of Sodium and Water in Muscle Following Severe Cold Injury

Abstract
The distribution of Na and water in normal muscle and in muscle removed from rabbits'' legs subjected to severe cold injury is reported. In 6 rabbits anesthetized with dial, the leg was immersed for 3 min. in a water-alcohol-ethylene glycol mixture at [long dash] 55 [degree]C. Blood samples and muscle samples from the normal and injured legs were taken 166-225 min. after injury. Water and Na detns. were made on samples of plasma and muscle. The gain of water by muscle after cold injury was 5-60%. The Na increase was 30% in one animal and 237-697% in the other 5. This disproportion between Na and water shows that Na is being redistributed.

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