Limiting the uncertainty in risk assessment by the development of physiologically based pharmacokinetic and pharmacodynamic models

This publication has 33 references indexed in Scilit:

• Rate and route of oxidation of acrylic acid to carbon dioxide in rat liver
  Fundamental and Applied Toxicology, 1992
• A physiologically based pharmacokinetic and pharmacodynamic model to describe the oral dosing of rats with ethyl acrylate and its implications for risk assessment
  Toxicology and Applied Pharmacology, 1992
• Sustainability of Forestomach Hyperplasia in Rats Treated with Ethyl Acrylate for 13 Weeks and Regression after Cessation of Dosing
  Toxicologic Pathology, 1991
• Cytogenetic studies of ethyl acrylate using C57BL/6 mice
  Mutagenesis, 1991
• Proliferative and genotoxic cellular effects in 2-acetylaminofluorene bladder and liver carcinogenesis: Biological modeling of the ED01 study
  Toxicology and Applied Pharmacology, 1990
• The Histopathological and Biochemical Response of the Stomach of Male F344/N Rats Following Two Weeks of Oral Dosing with Ethyl Acrylate
  Toxicologic Pathology, 1990
• Comparison of chromosome aberration frequency and small-colony TK-deficient mutant frequency in L5178Y/TK+/− -3.7.2C mouse lymphoma cells
  Mutagenesis, 1990
• Evaluation of uncertainty in input parameters to pharmacokinetic models and the resulting uncertainty in output
  Toxicology Letters, 1989
• Chronic Toxicity and Oncogenicity Bioassay of Inhaled Ethyl Acrylate in Fischer 344 Rats and B6c3f1 Mice
  Drug and Chemical Toxicology, 1985
• Potentiation of acrylate ester toxicity by prior treatment with the carboxylesterase inhibitor triorthotolyl phosphate (TOTP)
  Toxicology and Applied Pharmacology, 1981