Activities of Monomeric Insulin Analogs at Position A8 Are Uncorrelated with Their Thermodynamic Stabilities
Open Access
- 1 October 2001
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 276 (43) , 40018-40024
- https://doi.org/10.1074/jbc.m104634200
Abstract
No abstract availableKeywords
This publication has 40 references indexed in Scilit:
- Hierarchical Protein “Un-Design”: Insulin's Intrachain Disulfide Bridge Tethers a Recognition α-HelixBiochemistry, 2000
- The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helixJournal of Molecular Biology, 1998
- A structural switch in a mutant insulin exposes key residues for receptor binding 1 1Edited by A. R. FershtJournal of Molecular Biology, 1998
- Mapping the Functional Surface of Insulin by Design: Structure and Function of a Novel A-Chain AnalogueJournal of Molecular Biology, 1996
- Insulin-like Compounds Related to the Amphioxus Insulin-like PeptideBiochemistry, 1994
- Role of native disulfide bonds in the structure and activity of insulin-like growth factor 1: Genetic models of protein-folding intermediatesBiochemistry, 1993
- Steric requirements at position B12 for high biological activity in insulinBiochemistry, 1993
- X-ray analysis of the single chain B29-A1 peptide-linked insulin moleculeJournal of Molecular Biology, 1991
- Supernormal insulin: [D-PheB24]-insulin with increased affinity for insulin receptorsBiochemical and Biophysical Research Communications, 1982
- Receptor-binding region of insulinNature, 1976