DIAGNOSTIC RELIABILITY OF MI-MARK HELIX TECHNIQUE IN ENDOMETRIAL NEOPLASIA

  • 1 January 1983
    • journal article
    • research article
    • Vol. 62  (2) , 225-230
Abstract
To evaluate the diagnostic reliability of the Mi-Mark helix technique in endometrial neoplasia, 138 women with abnormal uterine bleeding underwent a prospective study of Mi-Mark sampling of the uterine cavity before dilatation and curettage. Of 138 patients, 42% had postmenopausal bleeding and 18% had perimenopausal bleeding. The acceptability of this procedure by patients and physicians was remarkable. All invasive endometrial carcinomas were detected by Mi-Mark cytology. The most serious limitation of this technique was its failure to detect a large number of hyperplasias without atypia. Examination of a cell block along with cytology would facilitate the histopathologic diagnosis, especially of hyperplasia. The results appear to justify the use of this procedure in high-risk patients.

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