4-Alkyl-thio- and -dithio-azetidinones from penicillins
- 1 January 1971
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society D: Chemical Communications
- No. 18,p. 1137-1139
- https://doi.org/10.1039/c29710001137
Abstract
Thiols react smoothly with penicillin sulphoxides to form 4-alkylthioazetidinones which, by treatment with phosphites or reaction with nucleophiles and alkyl iodides, afford 4-alkylthioazetidinones; some related reactions are also reported.Keywords
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