Electron Microscopic Definition of Surface Antigens of Group B Streptococcus

Abstract
Strains representing each of the five serologically distinct types of group B Streptococcus and variant strain 090R, which is devoid of type-specific polysaccharide, were studied by electron microscopy after incubation with various ferritin-conjugated antibodies. Ferritin-conjugated types Ia, II, and III antibodies localized on homologous cells in a pattern that defines the capsular location of the type Ia, II, and III polysaccharide antigen. Type Ib and Ie cells have surface antigens to which ferritinlabeled antibodies to both capsular polysaccharide and a common surface protein attach.

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