A DOUBLE-BLIND CROSS-OVER TRIAL OF PRENAZONE AND ASPIRIN IN THE MANAGEMENT OF RHEUMATOID ARTHRITIS
- 1 May 1975
- journal article
- clinical trial
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 14 (2) , 61-66
- https://doi.org/10.1093/rheumatology/14.2.61
Abstract
A double-blind cross-over trial of Prenazone 600 mg and Aspirin 4 g daily was carried out on 20 patients suffering with rheumatoid arthritis. The analgesic and anti-inflammatory activity was indistinguishable from that of aspirin under the conditions of the trial. Twelve patients expressed a general preference for Prenazone and six for aspirin. Prenazone appeared to be well tolerated and free from serious side-effects. These results suggest that it will be a useful drug in the management of rheumatoid arthritis.Keywords
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