Does liver biopsy overestimate liver iron concentration?
Open Access
- 1 September 2006
- journal article
- Published by American Society of Hematology in Blood
- Vol. 108 (5) , 1775-1776
- https://doi.org/10.1182/blood-2006-03-013482
Abstract
Consequently, the authors should have corrected their LICs measured by SQUID-BLS in order to analyze their data more accurately in this important publication on a novel oral chelator. We think that it is allowed to correct an initially false study assumption in a scientific paper. Measurements by BLS would have the highest impact especially in the LIC group of 7 mg Fe/g dry weight or less, although the final outcome may not change significantly. Moreover, we would hope to avoid giving potential readers the wrong impression that BLS underestimates LIC per se. One could, in fact, claim the opposite, as in our title, particularly in the case of deparaffinized samples.Keywords
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