Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome
Top Cited Papers
- 10 April 2011
- journal article
- research article
- Published by American Society of Clinical Oncology (ASCO) in Journal of Clinical Oncology
- Vol. 29 (11) , 1424-1430
- https://doi.org/10.1200/jco.2010.28.5148
Abstract
Purpose Medulloblastomas are heterogeneous tumors that collectively represent the most common malignant brain tumor in children. To understand the molecular characteristics underlying their heterog...Keywords
This publication has 35 references indexed in Scilit:
- The landscape of somatic copy-number alteration across human cancersNature, 2010
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1Cancer Cell, 2010
- Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1Nature, 2009
- CDK8 is a colorectal cancer oncogene that regulates β-catenin activityNature, 2008
- Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cellsThe EMBO Journal, 2008
- Assessing the significance of chromosomal aberrations in cancer: Methodology and application to gliomaProceedings of the National Academy of Sciences, 2007
- The 2007 WHO Classification of Tumours of the Central Nervous SystemActa Neuropathologica, 2007
- Metagene projection for cross-platform, cross-species characterization of global transcriptional statesProceedings of the National Academy of Sciences, 2007
- Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profilesProceedings of the National Academy of Sciences, 2005
- MicroRNA expression profiles classify human cancersNature, 2005