Is HIV out of control in the UK? An example of analysing patterns of HIV spreading using incidence-to-prevalence ratios
- 11 September 2006
- journal article
- research article
- Published by Wolters Kluwer Health in AIDS
- Vol. 20 (14) , 1898-1901
- https://doi.org/10.1097/01.aids.0000244213.23574.fa
Abstract
The incidence of diagnosed HIV in the UK is increasing. We calculated the incidence-to-prevalence ratio, IPR(t), which must exceed an ‘epidemic threshold’, the reciprocal of the mean infectious period, for sustained transmission to occur. For heterosexuals the IPR(t) is too low for a self-sustained UK epidemic, and incidence is driven by increasing prevalence, mostly from imported cases. For men who have sex with men the IPR(t) is around the epidemic threshold, suggesting that spread is not yet under control.Keywords
This publication has 12 references indexed in Scilit:
- HIV infections acquired through heterosexual intercourse in the United Kingdom: findings from national surveillanceBMJ, 2005
- Recent trends in HIV and other STIs in the United Kingdom: data to the end of 2002Sexually Transmitted Infections, 2004
- Definition and estimation of an actual reproduction number describing past infectious disease transmission: application to HIV epidemics among homosexual men in Denmark, Norway and SwedenEpidemiology and Infection, 2004
- Estimation of Annual HIV Transmission Rates in the United States, 1978???2000JAIDS Journal of Acquired Immune Deficiency Syndromes, 2004
- The role of sexually transmitted diseases in HIV transmissionNature Reviews Microbiology, 2004
- Improved Outcomes with Earlier Initiation of Highly Active Antiretroviral Therapy Among Human Immunodeficiency Virus–Infected Patients Who Achieve Durable Virologic Suppression: Longer Follow‐Up of an Observational Cohort StudyThe Journal of Infectious Diseases, 2003
- Prognosis of HIV-1-infected patients starting highly active antiretroviral therapy: a collaborative analysis of prospective studiesThe Lancet, 2002
- Sexual behaviour in Britain: partnerships, practices, and HIV risk behavioursThe Lancet, 2001
- Repeat HIV testing: high-risk behaviour or risk reduction strategy?AIDS, 2000
- Effects of HIV counseling and testing on sexual risk behavior: a meta-analytic review of published research, 1985-1997.American Journal of Public Health, 1999