ANTI-ACTIN ANTIBODIES OF HUMAN AND RABBIT ORIGIN

  • 1 January 1978
    • journal article
    • research article
    • Vol. C129  (2-3) , 245-254
Abstract
The production of actin antisera in rabbits was described and their reactions in immunological tests were compared with the results obtained with human anti-actin sera (smooth muscle antibodies). Although the sera reacted with different antigenic determinants of actin in immunoprecipitation and blocking experiments, the rabbit and human sera can be used for studies of cells with equal or similar results. A prerequisite was that the rabbit anti-actin titers were high. The difficulty in obtaining strong anti-actin sera in rabbits was confirmed.