Unsuspected Source of Vitamin K in Patients Treated with Anticoagulants: A Case Report

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Abstract
The administration of warfarin requires careful attention. The concurrent intake of drugs can either enhance or compete with its anticoagulant effect. Less frequently encountered are the effects from vitamin K added to food, intake of foods with naturally occurring high levels of vitamin K and diets deficient in vitamin K. We report a case in which loss of anticoagulant control was caused by a dietary supplement taken during a weight reducing diet by a patient who was receiving warfarin following a pulmonary embolus. A review of the literature reveals several similar cases. Amounts of vitamin K in food supplements and in foods with large amounts of naturally occurring vitamin K are tabulated along with suggestions for surveillance of patients taking anticoagulants.

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