Time-dependent inactivation of steroid C17(20) lyase by 17β-cyclopropyl ether-substituted steroids
- 1 January 1996
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 6 (1) , 97-100
- https://doi.org/10.1016/0960-894x(95)00566-c
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Androgen Formation by Cytochrome P450 CYP17. Solvent Isotope Effect and pL Studies Suggest a Role for Protons in the Regulation of Oxene versus Peroxide ChemistryBiochemistry, 1994
- Cytochrome P-450 C21scc: One enzyme with two actions: Hydroxylase and lyaseThe Journal of Steroid Biochemistry and Molecular Biology, 1991
- The mechanism of cytochrome P-450 dependent C–C bond cleavage: studies on 17α-hydroxylase-17,20-lyaseJournal of the Chemical Society, Chemical Communications, 1991
- 17β-(Cyclopropylamino)-androst-5-en-3β-ol, a selective mechanism-based inhibitor of cytochrome P45017α (steroid 17α-hydroxylase/C17–20 lyase)Biochemical and Biophysical Research Communications, 1989
- A normal phase high-performance liquid chromatography system for steroid 17α-hydroxylaseC17–20 lyase (cytochrome P-45021SCC) assaysAnalytical Biochemistry, 1988
- ESR studies on the radical cation mechanism of the ring opening of cyclopropylaminesJournal of the American Chemical Society, 1987
- Expression of Bovine 17α-Hydroxylase Cytochrome P-450 cDNA in Nonsteroidogenic (COS 1) CellsScience, 1986
- Mechanism-based inactivation of cytochrome P-450 by heteroatom-substituted cyclopropanes and formation of ring-opened productsJournal of the American Chemical Society, 1984
- Suicidal inactivation of cytochrome P-450 by cyclopropylamines. Evidence for cation-radical intermediatesJournal of the American Chemical Society, 1982
- Kinetic applications of electron paramagnetic resonance spectroscopy. 35. The search for a dialkylaminyl rearrangement. Ring opening of N-cyclobutyl-N-n-propylaminylJournal of the American Chemical Society, 1980