Preventing Preeclampsia

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Abstract
The report in this issue of the Journal by Sibai and colleagues1 highlights the search for a treatment to alter the incidence of preeclampsia. Hypertensive disorders complicate 10 to 12 percent of the 3.5 million pregnancies each year in the United States. The majority of the women with such disorders have preeclampsia (defined as hypertension and proteinuria beginning after 20 weeks of gestation), making preeclampsia the most common medical disease in pregnancy1. Although 85 percent of women with preeclampsia are nulliparous, multiparous women who have chronic hypertension antedating pregnancy have a 25 percent risk of superimposed preeclampsia. In developed . . .

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