The Drosophila clock gene per affects intercellular junctional communication
- 20 August 1987
- journal article
- retracted article
- Published by Springer Nature in Nature
- Vol. 328 (6132) , 686-691
- https://doi.org/10.1038/328686a0
Abstract
The per locus of Drosophila has been implicated in the control of behavioural rhythms. In fruitfly embryos and larvae per is expressed in salivary glands. Per mutations have striking effects on intercellular communication in salivary glands: gap junction channels are modulated so that their conductance varies inversely with the period of behavioural rhythms in the mutants. A similar effect on junctional communication in the nervous system may explain how per influences behavioural rhythms.Keywords
This publication has 19 references indexed in Scilit:
- P-element transformation with period locus DNA restores rhythmicity to mutant, arrhythmic drosophila melanogasterCell, 1984
- Molecular genetics of a biological clock in DrosophilaProceedings of the National Academy of Sciences, 1984
- Mosaic analysis of a Drosophila clock mutantMolecular Genetics and Genomics, 1983
- An improved in situ hybridization method for the detection of cellular RNAs in Drosophila tissue sections and its application for localizing transcripts of the homeotic Antennapedia gene complexThe EMBO Journal, 1983
- Cell-to-cell channels with two independently regulated gates in series: Analysis of junctional conductance modulation by membrane potential, calcium, and pHThe Journal of Membrane Biology, 1983
- Effects of dosage alterations at the per locus on the period of the circadian clock of DrosophilaMolecular Genetics and Genomics, 1982
- Elevation of ionic conductance between insect epidermal cells by β-ecdysone in vitroJournal of Insect Physiology, 1980
- EXPERIMENTAL POPULATION GENETICS OF MEIOTIC DRIVE SYSTEMS I. PSEUDO-Y CHROMOSOMAL DRIVE AS A MEANS OF ELIMINATING CAGE POPULATIONS OF DROSOPHILA MELANOGASTERGenetics, 1977
- Polyacrylamide gel electrophoresis in sodium dodecyl sulfate-containing buffers using multiphasic buffer systems: Properties of the stack, valid Rf− measurement, and optimized procedureAnalytical Biochemistry, 1977
- PHYSIOLOGY OF ELECTROTONIC JUNCTIONS*Annals of the New York Academy of Sciences, 1966