Interaction of metals in nickel‐sensitive patients
- 1 November 1993
- journal article
- Published by Wiley in Contact Dermatitis
- Vol. 29 (5) , 251-253
- https://doi.org/10.1111/j.1600-0536.1993.tb03559.x
Abstract
Nickel (Ni) dermatitis is, thought to involve the formation of complexes between Ni ions and suitable proteins. 4 groups of 30 subjects who gave positive patch test responses to NiSO4 2.9% aq. were each retested to 1 of 4 different solutions containing equimolar (0.1 M) amounts of NiSO4 plus MgSO4. NiSO4 plus CuSO4, NiSO4plus ZnSO4. and NiSO4 plus Li2SO4, respectively. The results, evaluated at 2 days by visual scoring only, demonstrated that the 4 metals exerted a different influence on the nickel reactions, perhaps interfering with one or more factors affecting the formation of Ni++ complexes.Keywords
This publication has 3 references indexed in Scilit:
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- Serum concentrations in nickel‐sensitive patients after prolonged oral administrationContact Dermatitis, 1990
- Nickel sensitivity: effects of prolonged oral intake of the elementContact Dermatitis, 1988