ADRENAL CORTEX AND WATER METABOLISM

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Abstract
Hormonal action of the adrenal cortex is discussed in the following connections: electrolyte metabolism; water excretion (in normal, dehydrated, and adrenalectomized animals and Addisonian patients); relation between water and electrolyte metabolism; antidiuretic hormone of neurohypophysis; anterior pituitary and posterior pituitary in diabetes insipidus; renal and extra-renal factors (e.g., internal fluid and electrolyte distribution, water intoxication, intestinal absorption, permeability); replacement therapy; adrenal medulla; thyroid; epileptic and other convulsions related to tissue hydration. In conclusion, the authors offer hypotheses to integrate and interpret the data.