Affected sib-pair analysis in endometriosis.
Open Access
- 1 July 2001
- journal article
- review article
- Published by Oxford University Press (OUP) in Human Reproduction Update
- Vol. 7 (4) , 411-418
- https://doi.org/10.1093/humupd/7.4.411
Abstract
This paper (i) reviews the current clinical and molecular genetic data which strongly suggest that endometriosis has a genetic basis; (ii) outlines the general principles of affected-sib pair analysis; and (iii) describes the Oxford Endometriosis Gene (OXEGENE) Study which aims, using a positional cloning approach, to identify susceptibility genes involved in the development of the disease.Keywords
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