The Use of Affinity in Chromosome Mapping

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Abstract
An association of a linkage HE marker with three linkage group V markers in Mus musculus has been investigated to test whether it can be explained on the hypothesis of "affinity" (D. Michie, Nature 171: 26-27 and M. E. Wallace, Nature 171: 27-28) and to provide data from which the position of the point in V responsible for the association may be located. Assuming this point to be the centromere, the use of this kind of data in chromosome mapping, and of other kinds theoretically obtainable in the near future, is demonstrated. A brief account is given of a process for obtaining metrical maps consistent with both affinity and linkage data, and a provisional map for linkage group V is given for the centromere and one terminus of the chromosome and for the markers tan belly, fidget and Danforth''s short tail.

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