Mutational Analysis and Molecular Modeling of the Allosteric Binding Site of a Novel, Selective, Noncompetitive Antagonist of the Metabotropic Glutamate 1 Receptor

This publication has 38 references indexed in Scilit:

• Tertiary templates for proteins: Use of packing criteria in the enumeration of allowed sequences for different structural classes
  Published by Elsevier ,2005
• A 5-HT4 Receptor Transmembrane Network Implicated in the Activity of Inverse Agonists but Not Agonists
  Published by Elsevier ,2002
• Rhodopsin: Insights from Recent Structural Studies
  Annual Review of Biophysics, 2002
• A model for the functioning of family 3 GPCRs
  Trends in Pharmacological Sciences, 2002
• Mapping the Agonist-binding Site of GABAB Type 1 Subunit Sheds Light on the Activation Process of GABABReceptors
  Published by Elsevier ,2000
• Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor
  Science, 2000
• Molecular tinkering of G protein-coupled receptors: an evolutionary success
  The EMBO Journal, 1999
• PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS
  Annual Review of Pharmacology and Toxicology, 1997
• Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F
  Nature, 1996
• A novel class of antagonists for metabotropic glutamate receptors, 7-(Hydroxyimino)cyclopropa[b]chromen-1a-carboxylates
  Bioorganic & Medicinal Chemistry Letters, 1996