Port-site metastasis after CO2 pneumoperitoneum
- 12 May 2004
- journal article
- research article
- Published by Springer Nature in Surgical Endoscopy
- Vol. 18 (7) , 1113-1117
- https://doi.org/10.1007/s00464-003-9150-5
Abstract
Port-site metastasis is a continuing problem in laparoscopic cancer surgery. To clarify the role of adhesion molecules in the development of port-site metastasis, particularly with regard to prevention, we performed experiments in which port-site metastasis was inhibited using antibodies against extracellular matrix proteins or the active Arg–Gly–Asp (RGD) peptide after CO2 pneumoperitoneum in a murine model.Keywords
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