The Activity of Ceftazidime Compared with Those of Aztreonam, Newer Cephalosporins and Sch 29482 against Nonfermentative Gram-Negative Bacilli

Publisher Website
Google Scholar
Abstract
The activity of ceftazidime was compared with those of aztreonam, newer cephalosporins and Sch 29482 against nonfermentative gram-negative bacilli. Ceftazidime was consistently more active (MIC < 8 μg) against the nonfermenters. Only Fla-vobacterium odoratum, F. spp., Pseudomonas alcaligenes, P. maltophilia and P. stutzeri demonstrated substantial resistance (MIC90 > 64 μg) to ceftazidime. Sch 29482 and ceftriaxone also exhibited good activity (MIC90 < 8 μg) against many of the nonfermenters. The broad activity of ceftazidime, however, makes it a potentially more useful therapeutic agent against these microorganisms.