BLACK HAIRY TONGUE ASSOCIATED WITH PENICILLIN THERAPY
- 12 August 1949
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 140 (15) , 1206-1208
- https://doi.org/10.1001/jama.1949.02900500014003
Abstract
Local reactions from the use of oral penicillin (glossitis, stomatitis and vesicular cheilitis) have frequently been described. However, another type of reaction has been reported in the foreign literaure1 but not in the American journals. The condition itself, black hairy tongue, has been known for many years, but its association with penicillin therapy is of recent note. I have observed this reaction to penicillin and believe that it is of sufficient interest to be documented. REPORT OF CASES Case 1.— In January 1948 a white woman aged 37 had been using penicillin lozenges for a sore throat. Discoloration of the tongue was observed a few days later. She was examined on the eighth day, at which time the tongue presented a velvety appearance and was brownish black on its medial and posterior portions. The filiform papillae were hypertrophied and bent like the nap of wet, heavy velvet when strokedKeywords
This publication has 1 reference indexed in Scilit:
- THE ABSORPTION, EXCRETION, AND DISTRIBUTION OF PENICILLIN 1Journal of Clinical Investigation, 1943