During the past decade a considerable number of articles have appeared in the world literature concerning the association of vascular abnormalities and trophic changes in soft tissues and bone. These are often referred to in the non-English literature as the Klippel-Trenaunay syndrome or Klippel-Trenaunay-Parkes Weber syndrome. At the risk of taking sides in the "lumper versus splitter debate" now current in medicine, it is our feeling that the entity described by Klippel and Trenaunay is essentially identical with what English and American authors are accustomed to referring to as the Parkes Weber syndrome. The following 2 cases are representative of these vascular anomalies and are also nicely illustrative of several of the many minor variations which may be seen. Report of Cases Case 1.— This 28-year-old white female was first seen in the University of Texas Medical Branch Outpatient Department on April 13, 1959. At that time she was in the