A new approach for EPR detection of hydroxyl radicals by reaction with sterically hindered cyclic amines and oxygen
Open Access
- 28 September 1987
- journal article
- Published by Wiley in FEBS Letters
- Vol. 222 (1) , 75-78
- https://doi.org/10.1016/0014-5793(87)80194-1
Abstract
Sterically hindered cyclic amines react with hydroxyl radicals in the presence of oxygen to yield stable nitroxide radicals which can be detected by EPR. This reaction provides a nonconventional spin‐trapping tool for detection of hydroxyl radicals.Keywords
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