Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2
- 5 September 2007
- journal article
- Published by Springer Nature in Nature
- Vol. 449 (7160) , 366-369
- https://doi.org/10.1038/nature06128
Abstract
Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and how science impacts upon all aspects of society and life.Keywords
This publication has 23 references indexed in Scilit:
- Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζCell Metabolism, 2006
- More TORC for the gluconeogenic engineBioEssays, 2006
- The CREB coactivator TORC2 is a key regulator of fasting glucose metabolismNature, 2005
- The CREB Coactivator TORC2 Functions as a Calcium- and cAMP-Sensitive Coincidence DetectorPublished by Elsevier ,2004
- Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradationProceedings of the National Academy of Sciences, 2003
- Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interactionNature, 2003
- Oxygen-Dependent Ubiquitination and Degradation of Hypoxia-Inducible Factor Requires Nuclear-Cytoplasmic Trafficking of the von Hippel-Lindau Tumor Suppressor ProteinMolecular and Cellular Biology, 2002
- CREB regulates hepatic gluconeogenesis through the coactivator PGC-1Nature, 2001
- Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)Science, 2001
- Regulatable Promoters for Use in Gene Therapy Applications: Modification of the 5′-Flanking Region of the CFTR Gene with Multiple cAMP Response Elements to Support Basal, Low-Level Gene Expression That Can Be Upregulated by Exogenous Agents That Raise Intracellular Levels of cAMPHuman Gene Therapy, 1996